May is one of the most pleasant months to explore the Czech Republic. With mild temperatures, blooming landscapes, and fewer crowds than the peak summer season, spring offers an ideal window to experience the country’s rich history, romantic towns, and breathtaking scenery. From the world-famous capital of Prague to hidden gems like Olomouc and Telč, there are countless opportunities to enjoy culture, architecture, nature, and warm hospitality.
In this guide, we’ll explore the 10 best cities in the Czech Republic to visit in May. Whether you’re drawn to medieval squares, spa towns, castles, or rolling vineyards, there’s a destination for every kind of traveler. And if you’re planning your spring adventure among the Best Places to Visit in Europe, make sure the Czech Republic tops your list!
1. Prague: The Magical Capital
No visit to the Czech Republic is complete without Prague. Nicknamed “The City of a Hundred Spires,” Prague is a stunning blend of Gothic, Baroque, and Romanesque architecture. May is perfect for exploring the Charles Bridge, Prague Castle, and the Old Town Square without the overwhelming crowds of summer. Spring flowers decorate the gardens at Petřín Hill, while Vltava River cruises offer a peaceful view of the city’s iconic skyline.
Don’t miss the May festivals, including the Prague Spring International Music Festival, which showcases classical performances in historic venues.
Top highlights:
- Walk across Charles Bridge at sunrise
- Tour the historic Prague Castle complex
- Explore the Jewish Quarter and its museums
2. Český Krumlov: A Fairytale Town
Located in South Bohemia, Český Krumlov looks like a scene from a storybook. Its 13th-century castle towers over a meandering river and a tangle of medieval streets. May is an ideal time to visit because the weather is just right for wandering through cobbled alleys, picnicking by the river, or enjoying a peaceful canoe ride.
The castle’s gardens bloom with spring flowers, offering spectacular views of the town and surrounding countryside.
Top highlights:
- Tour the UNESCO-listed Český Krumlov Castle
- Rent a canoe or raft on the Vltava River
- Stroll through the historic town square
3. Karlovy Vary: Spa Bliss in Spring
For those seeking wellness and relaxation, Karlovy Vary is a dream destination. Known for its healing thermal springs and elegant spa architecture, this town offers a rejuvenating retreat. In May, the fresh air and greenery of the Slavkov Forest invite you to hike, bike, or simply breathe deeply.
Indulge in the famous hot mineral waters, enjoy a spa treatment, and sample the town’s signature wafers and herbal liqueur, Becherovka.
Top highlights:
- Experience traditional spa treatments
- Walk the colonnades and sip mineral water
- Visit the Moser Glass Museum
4. Brno: Culture, Cafés, and Castles
Brno, the Czech Republic’s second-largest city, is a vibrant hub of students, creativity, and history. It has a relaxed atmosphere compared to Prague, but still boasts Gothic cathedrals, quirky museums, and a dynamic food and café scene. May brings blossoming parks, buzzing beer gardens, and plenty of festivals.
Be sure to tour the Špilberk Castle, explore the underground labyrinth, and admire the functionalist masterpiece of Villa Tugendhat.
Top highlights:
- Climb the tower at St. Peter and Paul Cathedral
- Explore the Ossuary and Brno underground
- Enjoy live music and events at city squares
5. Olomouc: Baroque Beauty and Student Vibes
Often overlooked, Olomouc is a baroque jewel filled with fountains, churches, and grand squares. It’s also a lively university town, which adds youthful energy to its historic charm. In May, the streets come alive with spring markets, outdoor cafés, and festivals.
The UNESCO-listed Holy Trinity Column is the city’s centerpiece, while flower-lovers will enjoy the spring display at Smetana Park.
Top highlights:
- Admire the astronomical clock on the Town Hall
- Visit the Olomouc Archdiocesan Museum
- Explore local beer pubs and cozy bistros
6. Telč: Renaissance Romance
In the heart of Moravia, Telč is a small town with a breathtaking Renaissance square that looks frozen in time. Surrounded by lakes and pastel-colored homes with arcaded fronts, it’s one of the most photogenic places in the country.
May’s mild weather invites visitors to relax in the gardens of Telč Castle or paddle on the nearby lakes. It’s a quiet and romantic retreat, ideal for couples or slow travelers.
Top highlights:
- Tour the Renaissance-style Telč Castle
- Stroll the UNESCO-listed town square
- Enjoy a paddle boat ride on Štěpnický Pond
7. Pilsen: The Birthplace of Pilsner Beer
Pilsen (Plzeň) is a must-visit for beer lovers. As the birthplace of the world-famous Pilsner lager, this West Bohemian city combines beer culture with colorful history. The Pilsner Urquell Brewery offers tours and tastings that are especially refreshing in May’s warm weather.
In addition to its brewing heritage, Pilsen features Gothic cathedrals, the largest synagogue in the Czech Republic, and several unique museums.
Top highlights:
- Take the Pilsner Urquell Brewery tour
- Climb the tower of St. Bartholomew’s Cathedral
- Explore the Pilsen Historical Underground
8. Kutná Hora: Silver City Rich in Gothic Splendor
Just an hour from Prague, Kutná Hora is perfect for a spring day trip. Once a center of silver mining, the town boasts wealth in the form of architecture. The Cathedral of St. Barbara and the eerie Bone Church (Sedlec Ossuary) attract visitors year-round, but May’s sunshine makes wandering its streets especially pleasant.
It’s also a good destination for those interested in Czech history, mining heritage, and unique spiritual experiences.
Top highlights:
- Visit the Gothic Cathedral of St. Barbara
- Tour the Sedlec Ossuary filled with human bones
- Walk along medieval streets with artisan shops
9. Znojmo: Wine, History, and River Views
Perched above the Dyje River in South Moravia, Znojmo is an ancient town surrounded by vineyards and rolling hills. Spring is the perfect time to sample local wines and hike through the nearby Podyjí National Park.
Its medieval charm includes a network of underground tunnels, Romanesque churches, and a Renaissance town hall tower with panoramic views.
Top highlights:
- Explore the scenic Dyje River valley
- Tour Znojmo Castle and rotunda
- Sample Moravian wines in cozy cellars
10. Třebíč: Sacred Heritage and Stunning Squares
Finally, Třebíč offers a peaceful getaway rich in cultural significance. It is home to a unique Jewish Quarter and a beautiful Christian basilica—both UNESCO sites that reflect centuries of peaceful coexistence. May adds fresh greenery and color to this historic setting, making it even more inviting.
Unlike more touristy towns, Třebíč offers a slower pace and a chance to deeply connect with local history and traditions.
Top highlights:
- Wander through the preserved Jewish Quarter
- Visit the Basilica of St. Procopius
- Enjoy scenic river walks and local cafés
Conclusion: Experience Czech Beauty in Bloom
Whether you’re seeking romance, relaxation, history, or cultural immersion, the Czech Republic in May is the perfect canvas for your spring adventure. Each city on this list offers something unique—from medieval charm and spa luxury to wine regions and vibrant festivals. These cities are not only among the Best Places to Go in Europe, but also living reminders of kindness, resilience, and timeless beauty.
As nature awakens and the spirit of joy fills the air, let your travels reflect the verse from Micah 6:8: “Act justly, love mercy, and walk humbly with your God.” May your journey through the Czech Republic in May be filled with kindness, culture, and connection.
